巨块及结节型原发性肝癌栓塞术后镇痛处理对比观察

The Analgesia Treatment after Transarterial Chemoembolization： Massive and Nodular Hepatocellular Carcinoma

目的探讨巨块及结节型原发性肝癌在肝动脉栓塞治疗后疼痛的控制效果及镇痛方法采用的基本原则。方法收集102例原发性巨块或结节型肝细胞癌随机分空白组，一级及二级镇痛组进行肝动脉栓塞治疗前后疼痛评级统计对比分析及评价镇痛效果。结果原发性肝癌栓塞治疗后有无镇痛具有显著性差别（P〈0．05），采用一级或二级镇痛无显著性意义（P〉0．05）。结论原发性肝癌栓塞治疗后疼痛应该及时干预，处理以一级镇痛为主，辅助以止酸、解痉的基础镇痛方法。

Objective To study the effect and basic principles of analgesia treatment after transarterial chemoembolization （TACE） on massive and nodular hepatoeellular carcinoma.Methods 102 patients with massive or nodular hepatocellular carcinoma were divided into three groups randomly,the contral group,the first and second analgesia grade group.The pain rating after TACE was analyzed with statistic method to evaluate analgesia effect. Results There was significant difference between groups with analgesia treatment and without analgesia treatment after TACE,but no significant difference between the first and second analgesia treatment group.Conclusion The pain after TACE needs to be intervened in time,and the main therapy method was the first grade analgesia assisted with basic treatment such as inhibitory gastric acid and antispasmodic.