水痘患儿血浆C反应蛋白检测及意义

Determination and significance of Serum CRP in Children with Varicella

目的:探讨C反应蛋白(CRP)测定在水痘患儿中的变化及临床意义。方法:对82例水痘患儿血浆CRP值与45例正常对照组(无感染)儿童血浆CRP值进行统计比较。结果:水痘患儿中合并细菌感染组CRP值明显高于单纯病毒感染组与正常对照组,CPR水平差异有显著性(P<0.01),单纯病毒感染组与正常对照组CRP值比较,差异无统计学意义(P>0.05)。结论:水痘患儿血浆CRP水平对鉴别是否合并细菌感染、判断病情变化与疗效、从而指导抗生素的正确使用具有一定价值。

Objective： To explore the variation and clinical significance of serum c-reactive protein（ CRP）in children with varicella. Methods： Serum CRP level were measured in eighty- two patients with varicella and forty- five normal children without infection （control group）,to analyse their results. Results： The serum concentrations of CRP in varicella group complicated with bacterial infection were significantly higher than those in the case group with simplex infection and control group（both P〈0.01 ）.There is no significant difference between the case group with simplex infection and control group（P〉0.05）. Conclusions： Measurement of serum CRP has certain value for diagnosing merge of bacterial infection, evaluating change of illness state, and instructing rational use of antibiotics in children with varicelia.