锰离子作为影像增强剂对神经系统功能的影响

Effect of manganese as image intensifier on the function of nervous system

随着锰在影像学和实验研究中的不断应用,其毒性损伤已经成为近期人们研究的热点。大量研究证明,锰作为机体微量元素,堆积后的损伤主要表现于神经系统。我们从锰作为影像增强剂这一角度对其给药方式、机体损伤和损伤机制的研究做一综述。

As the manganese has been applied continually in the imaging studies and experimental researches, its toxic injury has been a hotspot. Many studies have demon-strated that the damage of large accumulation of mangan-ese, as a body trace element, is expressed mainly in the nervous system. This article will summarize the papers concerned with the delivery method, body injury and neurotoxic mechanism of manganese, while man-ganese was applied as an image intensifier. 