口服轮状病毒活疫苗的社区应用效果评价

Study on the Effectiveness of Rotavirus Vaccine for Oral Use to Prevent Diarrhea in the Community

目的探讨口服轮状病毒活疫苗在社区卫生服务中的应用效果,以提高预防接种率,促进社区卫生服务疾病预防工作。方法将在社区健康服务中心建立健康档案的2000名6月龄～3周岁的儿童随机分成服苗组和对照组,进行轮状病毒腹泻的发病情况比较。结果服苗组发病率为2.1%,同期对照组的发病率为8.4%,两者差异有统计学意义(P<0.01),且服苗组的发病程度明显低于对照组。结论口服轮状病毒活疫苗预防儿童轮状病毒腹泻效果显著。

OBJECTIVE To explore the effectiveness of rotavirus vaccine for oral use to prevent diarrhea of the children and provide the scientific base for prevention of diarrhea. METHODS A community test was designed, in which Cases were children who were from 6- monthes to 3-years old, and accept rotavirus vaccine for oral use in Shenzhen City in 2000, and the controls were chosen by random from the children who were unwilling to take the vaccine. RESULTS The diarrhea incidence of case group was 2.1%, and the control group was 8.4%, and the difference has statistical significance（P〈0.01）. CONCLUSION This study showed that the rotavirus vaccine for oral use had highly effective in preventing diarrhea in the children.