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葡萄糖调节受损的研究现状 被引量：5

Impaired glucose regulation
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摘要 葡萄糖调节受损（IGR）是介于正常血糖与糖尿病之间的一种中间状态.它同样具有2型糖尿病的两大基本特征：胰岛素抵抗和β细胞分泌功能受损.但它包括的两种血糖异常状态即空腹血糖受损和糖耐量减低具有不同的胰岛素抵抗和β细胞分泌功能特征及流行病学特征.我国普通成年人中15.5%发生IGR.IGR独立于代谢综合征的其他组分而与动脉粥样硬化性心血管疾病密切相关,采取生活方式及适当药物早期干预IGR可有效防治糖尿病及心血管疾病的发生. Impaired glucose regulation （IGR） is a condition between normal blood glucose and diabetes mellitus. IGR also has two basic features of type 2 diabetes mellilus： insulin resistance and islet β cell dysfunction. On the other hand, IGR includes two different abnormal glycetnia conditions-impaired fasting glucose （IFG） and impaired glucose tolerance （IGT）, which have distinct degrees on insulin resistance and islet β cell dysfunction and different epidemiological features. 15. 5% of Chinese ordinary adults developed ICR. IGR is significantly related with atherosclerotic cardiovascular diseases that independent of components of metabolic syndrome. Lifestyle intervention and relevant pharmacotherapy earlier are effective in reducing the incidence of diabetes and cardiovascular diseases in subjects with pre-diabetes.
作者 张静漪 刘树琴
机构地区 安徽省马鞍山市中心医院特种病房 安徽医科大学附属医院内分泌科
出处 《国际内分泌代谢杂志》 2010年第3期195-198,共4页 International Journal of Endocrinology and Metabolism
关键词 葡萄糖调节受损 胰岛素抵抗 胰岛Β细胞 代谢综合征 动脉粥样硬化 Impaired glucose regulation Insulin resistance Islet β cell Metabolic syndrome Atherosclerosis
分类号 R587.1 [医药卫生—内分泌]
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参考文献19

  • 1International Expert Committee.International Expert Committee report on the role of the Alc assay in the diagnosis of diabetes.Diabetes Care,2009,32:1327-1334.
  • 2American Diabetes Association.Diagnosis and classification of diabetes mellitus.Diabetes Care,2010,33:S62-S69.
  • 3Abdul-Ghani MA,Tripathy D,DeFronzo RA.et al.Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose.Diabetes Care,2006,29:1130-1139.
  • 4Novoa FJ.Varillas VK.Boronat M,et al.Differences in cardiovascular risk factors,insulin resistance,and insulin secretion in individuals with normal glucose tolerance and in subjects with impaired glucose regulation.The Telde Study.Diabetes Care,2005,28:2388-2393.
  • 5Abdul-Ghani MA,Jenkinson CP,Richardson DK,et al.Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance:Results from the veterans administration genetic epidemiology study.Diabetes,2006,55:1430-1435.
  • 6Cynthia MF,Andrew PG.Limited value of the homeostasis model assessment to predict insulin resistance in older men with impaired glucose tolerance.Diabetes Care,2001,24:245-249.
  • 7Meyer C,Pimenta W,Woerle HJ,et al.Different mechanisms for impaired fasting glucose and impaired postprandial glucose tolerance in humans.Diabetes Care,2006,29:1909-1914.
  • 8Muhammad A,Abdul-Ghani,Christopher P,et al.Insulin secretion and action in subjects with impaired fasting glucose and im-paired glucose tolerance:Results from the Veterans Administration Genetic Epidemiology Study.Diabetes,2006,55:1430-1435.
  • 9Hong J,Gui MH,Gu WQ.et al.Differences in insulin resistance and pancreatic B-cell function in obese subjects with isolated impaired glucose tolerance and isolated impaired fasting glucose.Diabet Med,2008,25:73-79.
  • 10The DECODE Study Group.Age-and sex-specific prevalence of diabetes and impaired glucose regulation in 13 European cohorts.Diabetes Care,2003,26:61-69.

二级参考文献30

  • 1施曼珠,张俊清,钱荣立,杨建梅,贾培红,张树彬,欧阳福珍,邓正明,李琼芳,张少石,秦淑珍,康新满,李美莲,李经,胡伟,鲁梅花.NIDDM患者微量白蛋白尿与冠心病的关系[J].中国糖尿病杂志,1996,4(3):131-134. 被引量：21
  • 2WHO:The World Health Report.World Health Organization,Geneva,1998.
  • 3Harris MI,Flegal KM,Cowie CC,et al.Prevalence of diabetes,impaired fasting glucose,and impaired glucose tolerance in US adults.Diabetes Care,1998,21:518-524.
  • 42009,4th IDF DIABETES ATLAS.Available from:http://www.diabetesatlas.org/.
  • 5Nathan DM,Cleary PA,Backlund JY,et al.Intensive diabetes treatment and cardiovascular disease in patients with type 1diabetes.N Engl J Med,2005,353:2643-2653.
  • 6American Diabetes Association.Standards of medical care in diabetes-2010.Diabetes Care,2010,33(Suppl 1):S11-S61.
  • 7Yang W,Lu J,Weng J,et al.Prevalence of diabetes among men and women in China.N Engl J Med,2010,362:1090-1101.
  • 8Califf RM,Boolell M,Haffner SM,et al.Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance:Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research(NAVIGATOR)Trial.Am Heart J,2008,156:623-632.
  • 9Expert Committee on the Diagnosis and Classification of Diabetes Mellitus.Report of the expert committee on the diagnosis and classification of diabetes mellitus.Diabetes Care,1999.22:S5-S19.
  • 10Alberti KGMM,Zimmet PC,,for the WHO Consultation.Definition,diagnosis,and classification of diabetes mellitus and its complications.Part 1:diagnosis and classification of diabetes mellitus.Geneva:World Health Organization,1999.

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二级引证文献34

国际内分泌代谢杂志
2010年 第3期

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