消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响

Influence and of Endometriosis Model Mouse’s Liquid of Abdominal Cavity PGF_(2α) and Serum CA_(125) Which Treated with Xiaozheng Decoction

目的:探讨消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素(PGF2α)和血清卵巢癌表面抗原(CA125)的影响。方法:实验分为生理盐水组,西药对照组,中药高剂量组,中药低剂量组,每组10只,采用ELISA法,观察子宫内膜异位症模型大鼠腹腔液PGF2α血清CA125水平浓度。结果:消癥汤能够降低子宫内膜异位症模型鼠血清CA125水平和腹腔液中PGF2α含量,对异位子宫内膜具有一定的抑制作用。结论:消癥汤能降低血清CA125水平、腹腔液中PGF2α含量,抑制异位子宫内膜的异常增生。

Objective：To observe the effect of Xiaozheng Decoction（XZD） resolve in treating endometriosis model mouse and to explore its Liquid of abdominal cavity PGF2α、serum CA125.Method：Divide into four groups,the group treated with physiological saline,the group treated with Western medicine,the group treated with traditional Chinese medicine of high dosage,and the group treated with traditional Chinese medicine of low dosage,each group with ten mouses.By ELISA to observe endometriosis model mouse＇s serum CA125andliquid of abdominal cavity PGF2α.Result：XZD reduce the serum CA125,liquid of abdominal cavity PGF2α,of endometriosis model mouse and has some restrained function for endometriosis.Conclusion：XZD has an effect may be achieved by reducing the serum CA125,liquid of abdominal cavity PGF2α,restraining unusual proliferation of endometriosis.