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瘦素和转化生长因子β1参与2型糖尿病大鼠肾小管上皮细胞转分化 被引量:3

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摘要 2型糖尿病(T2DM)患者早期即存在高血清瘦素,其是否参与T2DM肾小管上皮细胞转分化(EMT)过程,以及它与经典的EMT诱导剂TGF-β1之间的关系,目前国内外尚未见报道.因此,我们通过观察T2DM大鼠血清瘦素和肾脏瘦素受体(OB-R)、TGF-β1和α-平滑肌肌动蛋白(α-SMA)的变化,探讨瘦素在糖尿病肾病(DN)的EMT中作用.
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2010年第6期466-467,共2页 Chinese Journal of Nephrology
基金 2006 年青岛市科技发展计划项目(06-2-2-3-nsh-3)
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参考文献5

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共引文献214

同被引文献34

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