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盐酸米诺环素软膏联合α-糜蛋白酶治疗急性牙周脓肿30例临床观察 被引量:7

TREATMENT OF ACUTE PERIODONTAL ABSCESS IN MINOCYCLINE COMBINED α-CHYMOTRYPSIN
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摘要 目的观察盐酸米诺环素软膏和α-糜蛋白酶联合治疗急性牙周脓肿的效果。方法选择来我院就诊的急性牙周脓肿患者60例,随机分为盐酸米诺环素软膏联合α-糜蛋白酶观察组和碘甘油对照组,每组各30例,观察组行牙周袋内刮治并用α-糜蛋白酶溶液袋内冲洗后牙周袋内注入盐酸米诺环素软膏,对照组行牙周袋内刮治后在牙周袋内涂滴2%碘甘油,观察治疗前后临床症状和临床指标(PD、GI、SBI)的变化。结果治疗后1周,观察组与对照组总有效率分别为90.00%,53.33%,差异有统计学意义(P<0.001);经治疗后2周,观察组与对照组总有效率分别为100%、60%,差异有统计学意义(P<0.01)。结论急性牙周脓肿在常规基础治疗基础上,局部应用盐酸米诺环素软膏和α-糜蛋白酶是一种安全、有效、简便的辅助治疗方法。 Objective To observe the effect of minocycline ointment combined α-chymotrypsin on acute periodontal abscess.Methods 60 patients with acute periodontal abscess were equally and randomly divided into two groups,minocycline combined a-chymotrypsin experimental group and iodine glycerin control group.The cases in the experimental group were treated by the periodontal pockets scaling and washed with a-chymotrypsin solution.Minocycline ointment was injected into periodontal pockets.The other group was treated by the periodontal pockets scaling and drops of 2% iodine glycerin.Then the changes of the clinical symptoms and clinical indicators before and after treatment were observed.Results The total effective rate of the experimental group and control group were 90% and 53.33% after one week treatment.There was statistically significant difference between the two groups(P0.01).The total effective rate of the experimental group and control group were 100% and 60% after two-week treatment.There was statistically significant difference between the two groups(P0.01).Conclusion The treatment of acute periodontal abscess using minocycline combined a-chymotrypsin is a safe,effective and simple auxiliary way based on the conventional basic treatment.
出处 《中国煤炭工业医学杂志》 2010年第6期841-842,共2页 Chinese Journal of Coal Industry Medicine
关键词 牙周脓肿 盐酸米诺环素软膏 Α-糜蛋白酶 periodontal abscess minocycline ointment α-chymotrypsin
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