消癥汤对子宫内膜异位症模型大鼠腹腔液PGF_(2α)和血清CA_(125)水平的影响

Influence and of Endometriosis Model Mouse's Liquid of Abdominal Cavity PGF_(2α) and Serum CA_(125) which Treated with Xiaozheng Decoction (XZD)

目的:探讨消癥汤对子宫内膜异位症模型大鼠腹腔液PGF2α和血清CA125的影响。方法:实验分为生理盐水组,西药对照组,中药高剂量组,中药低剂量组,每组10只,采用ELISA法,观察子宫内膜异位症模型大鼠腹腔液PGF2α及血清CA125水平浓度。结果:消癥汤能够降低子宫内膜异位症模型鼠血清CA125水平、腹腔液中PGF2α含量,对异位子宫内膜具有一定的抑制作用。结论:消癥汤能降低血清CA125水平、腹腔液中PGF2α含量,抑制异位子宫内膜的异常增生。

Objective：To observe the effect of Xiaozheng decoction（XZD） resolve in treatingendometriosis model mouse and to explore its Liquid of abdominal cavity PGF2a、serum CA125.Method：Divide into four groups,the group treated with physiological saline,the group treated with western medicine,the group treated with traditional Chinese medicine of high dosage,and the group treated with traditional Chinese medicine of low dosage,each group with ten mouses.By ELISA to observe endometriosis model mouse＇s serum CA125 andliquid of abdominal cavity PGF2a.Result：XiaoZheng Decoction （ XZD ） reduce the serum CA125,liquid of abdominal cavity PGF2a of endometriosis model mouse and has some restrained function for endometriosis.Conclusion：XZD has an effect may be achieved by reducing the serum CA125,liquid of abdominal cavity PGF2a,restraining unusual proliferation of endometriosis.