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TCF7L2基因多态性与合肥地区人群2型糖尿病的关联性研究 被引量：2

Association between polymorphisms of transcription factor 7-like 2 gene and type 2 diabetes mellitus in Hefei district
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摘要 探讨TCFTL2基闰多态性与合肥地区人群2型糖尿病遗传易感性的关系。结果显示TCF7L2基因的微卫星（DG10S478）多态性与合肥地区人群2型糖尿病发病风险无明显相关（P〉0．05），在该地区人群2型糖尿病的发病中并非主效基因。 To explore the association between polymorphisms of transcription factor 7-like 2 gene （TCF7L2） and type 2 diabetes mellitus in Hefei district. The results suggest that the genetic variation DG10S478 in the TCFTL2 gene was not associated with type 2 diabetes mellitus in Hefei district （P〉0.05）. However, its attribution to the susceptibility of type 2 diabetes mellitus in Hefei is not important.
作者 戴武 曹永红 王长江 王佑民 刘克梅 韩晓芳 叶军 刘玲 翟斐
机构地区 合肥市第二人民医院内分泌科 安徽医科大学第一附属医院内分泌科
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2010年第8期676-678,共3页 Chinese Journal of Endocrinology and Metabolism
基金 合肥市科技局重点立项项目【合科合同（卫）字2008（1014）号】
关键词 糖尿病 2型 TCFTL2基因 DG10S478 关联 Diabetes, type 2 TCF7L2 gene DG10S478 Association
分类号 R587.1 [医药卫生—内分泌]
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参考文献20

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二级参考文献148

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中华内分泌代谢杂志
2010年 第8期

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