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稳定性和非稳定性颈动脉斑块及相关因素与脑梗死关系的分析 被引量:9

Analysis on the relationship between the stable,unstable carotid artery plaque,its relevant elements and the cerebral infarction
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摘要 目的探讨颈动脉粥样硬化稳定性和非稳定性斑块及相关因素与脑梗死发病率的关系。方法将268例经高频超声检查有颈动脉粥样硬化斑块,又做了脑CT检查的住院患者,分成稳定性斑块组和非稳定性斑块组,同时收集了患者有无高血压病、糖尿病及高血脂症等临床资料进行分析。结果发生脑梗死者,稳定性斑块共103例(70.1%),非稳定性斑块共93例(76.9%),二者脑梗死的发病率及稳定性斑块和非稳定性斑块分别伴随的高血压病、糖尿病和(或)高脂血症均无显著差异(P>0.05)。结论颈动脉粥样硬化稳定性与非稳定性斑块患者,如若为高龄,同时又伴随有高血压病和(或)糖尿病与高脂血症等相关因素,其脑梗死的发病率可能出现无显著差异现象。 Objective To investigate the relationship between the carotid artery atheroselerosis plaque and the cere- bral infarction. Methods We analyzed the 268 in - patients diagnosed with carotid artery atheroselerosis which were divided into the stable plaque group and the unstable plaque group. Meanwhile, we collected some of them with hypertension, diabetes and hyper]ipidemia or not by high - frequency ultrasound and CT scan to analysis. Results Cerebral infarction was found on 103 patients(70.1% )among the stable plaque group and on 93 patients (78.9%) among the unstable plaque group. There was no significant difference in the incidence of cerebral infaetion, suffering hypertension, diabetes and hyperlipidemia between stable plaque group and unstable plaque group (P 〉 0.05 ). Conclusion Cerebral infarction is found in those two groups with no significant differences,if those in - patients were old and, suffering hypertension and diabetes and hyperlipidemia, etc.
作者 徐介民
机构地区 四川省建筑医院
出处 《中国医学创新》 CAS 2010年第26期36-37,共2页 Medical Innovation of China
关键词 高频超声 颈动脉粥样硬化 稳定性斑块 非稳定性斑块 脑梗死 High - frequency ultrasound Carotid artery atheroselerosis Stable plaque Unstable plaque Cerebral infaction
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  • 1黄品同,黄福光,孙海燕,田新桥,杨琰,吕夕明,唐疾飞,张超.超声造影对颈动脉粥样斑块内新生血管的血流动力学研究[J].中华超声影像学杂志,2007,16(1):40-42. 被引量:60
  • 2孙海燕,黄品同,黄福光,田新桥,杨琰,吕夕明.超声造影评价颈动脉粥样硬化斑块的初步研究[J].中华超声影像学杂志,2007,16(3):219-221. 被引量:41
  • 3Bots ML, Hoes AW,Koudstaal PJ, et al. Common carotid intima media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation, 1997,96(5):1432-1437.
  • 4Stou G,Jander S, Sitzer M, et al. Unstabie carotid stenosis:an inflammatory disease. Nervenarzt, 2000,71: 955-962.
  • 5Nagai Y, kitagawa K, Sokaguchi M,et al. Significance of earlier caroid atherosclerosis for strok subtypes. Stroke, 2001,32 (8):1780-1785.
  • 6Jeziorska M,Woolley DE. Neovascularization in early atheroselerotic lesions of human carotid arteries:its potential contribution to plaque development. Hum Pathol, 1999,30 : 919-925.
  • 7Virmani R,Kolodgie FD,Burke AP, et al. Atherosclerotic plaque progression and vulnerability to rupture:angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol, 2005,25 : 2054-2061.
  • 8Coombs BD,Rapp JH,Ursell PC,et al. Structure of plaque at carotid bifurcation: high-resolution MRI with histological correlation. Stroke, 2001,32: 2516-2521.
  • 9Cipollone F, Prontera C, Pini B, et al. Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E (2)-dependent plaque instability. Circulation, 2001, 104: 921- 927.
  • 10Pedro R. Moreno, MD, K. Raman Purushothaman, MD, Valentin Fuster,MD,PhD, et al. Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta. Circulation, 2004,110 : 2032-2038.

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