摘要
原发性肾病综合征是儿科常见的慢性疾病,目前对其病因、发病机制尚未完全阐明。本文从体液免疫、细胞免疫、肾脏固有细胞参与的免疫对原发性肾病综合征的致病机制予以探讨,有利于更清楚地认识原发性肾病综合征的病因和发病机制,以指导临床对激素、免疫抑制剂及免疫调节剂的应用。
Primary nephritic syndrome was one of the most common chronic disease of children.However,its causes and pathogenesis were not well understood.Therefore,there was no effective treatment available for patients with primary nephritic up to now.This article will review the pathogenic mechanism of primary nephritic syndrome from humoral immunity,cellular immunity and the immunity involved in intrinsic renal cells.It is beneficial to have a better understanding from the cause and mechanism of primary nephrotic syndrome to guide the therapeutic strategies from corticosteroids,immunosuppressants and immunomodulator.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第30期3461-3463,共3页
Chinese General Practice
关键词
肾病综合征
免疫
致病机制
儿童
Nephritic syndrome
Immunity
Pathogenic mechanism
Children