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输血相关性移植物抗宿主病研究进展 被引量:1

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摘要 输血相关性移植物抗宿主病(Transfusionassociated graft versus host diseases,TA-GVHD)是输入含有免疫活性淋巴细胞的血液(或成分)后发生的一种致命的输血并发症,其发病率不清楚,但病死率高达85%以上。TA-GVHD最初是60年代中期由Hathaway等报道在2例免疫缺陷病儿童输注富含白细胞血浆和全血后引起的GVHD,但随后在某些非免疫功能损害病人中的发病率也在不断引起重视。到目前为止,TA-GVHD尚无有效的治疗方法,因此通常以预防为主。本文就TA-GVHD的发病机理。
作者 张献清 王军
出处 《陕西医学杂志》 CAS 1999年第6期348-351,共4页 Shaanxi Medical Journal
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