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咪唑安定和异丙酚复合全麻的临床观察 被引量:1

ClinicalStudy on Midazolam and Propofol Combined Anesthesia
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摘要 观察了咪唑安定( Ⅰ组) 、异丙酚( Ⅱ组) 和2 药合用( Ⅲ组) 对循环指标、应激反应及苏醒时间的影响。结果显示:Ⅰ、Ⅱ组麻醉诱导后SBP 明显下降,Ⅲ组变化不明显。麻醉维持期循环稳定。意识恢复时间Ⅱ组(5 ~13 min) 和Ⅲ组(7 ~20 min) 相近,Ⅰ组最长(35 ~80 min) 。Ⅰ组术中血管紧张素Ⅱ及醛固酮较麻醉前明显升高( P< 0 .05) ,Ⅱ、Ⅲ组则相对稳定。提示:咪唑安定与异丙酚合用不仅有协同作用,且可取长补短,属临床可供选用的麻醉方法之一。 In order to investigate the effects of midazolam only ( Ⅰgroup) 、propofol only ( Ⅱ group) and midazolam combined with propofol ( Ⅲgroup) on circulation ,stress and awakening time . Afterinduction SBPdecreased significantly in Ⅰand Ⅱgroups,butthere was no remarkable changein Ⅲgroup . The circulation was stable during anesthesia maintenance . Ⅱand Ⅲgroups had approximate awakening time ( Ⅱgroup 5 ~13 min , Ⅲgroup 7 ~20 min) and Ⅰgroup was 35 ~80 min . Angitensin Ⅱand aldosteronelevels changed greatly than pre anesthesiai,but there was only little change in Ⅱand Ⅲgroups . Midazolam combined with propofol not only had cooperated effects but also could overcome each defect.It was a selectable anesthesia method for clinical use .
出处 《首都医科大学学报》 CAS 1999年第4期282-284,共3页 Journal of Capital Medical University
关键词 咪唑安定 异丙酚 应激反应 全身麻醉 midazolam propofol stress
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