幽门螺杆菌感染对胃食管反流病保护机制的研究现状

The Protection Mechanism of Helicobacter Pylori Infection to Gastroesophageal Reflux Disease

胃食管反流病(GERD)是一种常见的上消化道动力障碍性疾病,严重影响人们的生活质量,且发病率呈上升趋势,越来越受到重视。幽门螺杆菌(Hp)感染对GERD的影响是近来年消化病学领域的研究热点。有研究显示Hp感染对GERD并无影响,也有研究报道Hp感染可以促进GERD的发生,但是国内外大部分的研究结果支持Hp感染可能对GERD具有保护作用。

Gastro-esophageal reflux disease is a common upper gastrointestinal tract dyskinesis disease.It influences the quality of people′s life seriously.The incidence rate is increasing.People pay more attention to gastro-esophageal reflux disease（GERD）.Recently,the influence of Helicobacter pylori infection to GERD is a research hot in Digestion study field.Some studies demonstrate that Helicobacter pylori infection has no influence to GERD.There are also some studies demonstrate that Helicobacter pylori infection can promote GERD.While most studies support that Helicobacter pylori infection may play a protect role in GERD.