耳鸣治疗的影响因素分析

Regression Analysis of the Effects of Tinnitus

目的通过电针刺激与口服药物进行耳鸣临床治疗的观察,评估对耳鸣患者采取干预措施的价值,并运用多元线性回归法分析治疗中的可能影响因素。方法 将病程大于3个月的主观性耳鸣患者80例,根据就诊顺序分为针灸治疗组与药物治疗组(每组40例),针灸组采用听宫穴为主穴并通脉冲刺激,每次15min,每日1次,20次为一疗程;口服组给予甲钴胺、银杏叶片连续20d为一疗程。疗程结束后根据疗效评定标准评价疗效,分析影响耳鸣临床疗效的可能因素。结果 ①2组有效率分别为52.5%和37.5%,组间疗效差异无统计学意义(P=0.082);②由回归方程可知:疗效与耳鸣持续时间呈负相关,具有统计学意义(P=0.000)。结论 对耳鸣患者采取干预治疗措施是有意义的,治疗方案应遵循综合性、个体化,早期进行治疗者预后更为乐观。

Objective：To observe the clinical efficacy of electroacupuncture at acupoints in front of ears with drug treatment on tinnitus,to evaluate the interventions,and to analyze the possible factors influencing the treatment with the method of multivariate linear stepwise regression.Methods：Eighty cases with chronic subjective tinnitus in whom ringing in the ears was the first complaint and course of more than 3 months were enrolled in this study.The patients were randomly divided into acupuncture group and drug control group,40 cases in each.In the acupuncture group the main points in front of ears were adopted and were treated through pulse stimulation,the needles were left for fifteen minutes each time,once a day and twenty times formed a course.The patients in the drug control group were given oral tablets,Ginkgo and Mecobalamin for 20 consecutive days.After the treatment,evaluation was made according to standards,and analyses were performed for factors that may affect efficacy of tinnitus.Results：Efficiency of the two groups were 52.5% and 37.5%,there was no significant difference（P=0.082）.The effect Y had a negative correlation with the course X2.Conclusion：Intervention with both the acupuncture and drug treatments was effective for patients with tinnitus.