小儿毒鼠强中毒血清LDH、CK变化分析

Analysis of changes in serum enzymes in children with acute tetramine poisoning

目的 :探讨急性毒鼠强中毒儿童的血清LDH、CK变化水平及临床意义。方法 :测定 116例急性毒鼠强中毒患儿血清LDH、CK变化并与健康儿童 5 0例作对照。结果 :中毒组LDH和CK值分别为 2 6 6 77± 10 1 7u/L和 833 74± 46 5 2 1u/L ,与对照组 177 6± 6 7 42u/L和 6 5 34± 36 2 1u/L相比 ,有显著差异。结论 :LDH、CK活性增高与病情的轻重和转归有密切关系 ,测定LDH。

Objective:To investigate the changes and clinical significances in serum lactate dehydrogenase (LDH) and creatine phosphokinase (CK) levels in children with acute tetramine poisoning.Methods:Serum LDH and CK were determined by speed rate method in 116 cases and 50 healthy children served as controls.Results:Serum LDH and CK levels were 266 77±101 7 u/L and 833 74±465 21u/L respectively in patients with acute tetramine poisoning,which were markedly higher than those in normal controls(177 6±67 42u/L and 65 34±36 21u/L).Conclusions:High levels of LDH and CK might be related to the severity of disease in children with acute tetramine poisoning.Contents of serum LDH and CK can serve as useful parameters to reflect the severity of disease and predict the prognosis.