空气污染对胎儿生长发育的影响及作用机制

Impact of air pollution on fetal development

近十年来,已经有了越来越多关于空气污染与胚胎发育影响的研究报告。流行病学观察和实验研究等均显示,产前暴露于空气污染与低出生体重(LBW)、早产(PTB)、胎儿宫内生长受限(IUGR)、先天性缺陷、胎肺发育延迟、死胎、死产和新生儿死亡等不良妊娠结局有关。本文回顾空气污染物胎儿生长发育的影响及其作用机制的研究进展。

Numerous researches on the health effects of air pollution have been reported during the last decade.Epidemiological and experimental studies have shown that prenatal exposure to air pollutants is associated with adverse birth outcome including low birth weight（LBW）,preterm birth（PTB）,intrauterine growth restriction（IUGR）,congenital defects,prolonged fetal lung growth,stillbirth,fetal death and neonatal death.This article retrospectively overviews the influence of air pollution on the fetal development and its mechanisms.