补肾中药治疗骨质疏松的实验研究进展

Emperimentcal study of advancement of Chinese kidney-tonifying drugs for treating osteoporosis

动物模型对中医药防治骨质疏松的实验研究是十分必要的。骨质疏松症动物模型主要有去卵巢致骨质疏松动物模型、药物致骨质疏松动物模型、营养性骨质疏松模型、甲状旁腺切除法致骨质疏松动物模型等。中医药防治骨质疏松多从补肾入手,许多传统的补肾中药在防治原发性骨质疏松症有明显效果,如淫羊藿、补骨脂、骨碎补、巴戟天、菟丝子、蛇床子等。相对于单味药来说,方剂配伍更能发挥药物的作用。现代学者在补肾复方制剂防治骨质疏松的实验研究有了深入进展。中药防治骨质疏松整体治疗效果好,副作用小,具有广阔的前景。

Osteoporosis（OP）animal model is very necessary in the experimental research of OP.OP animal model includs ovariectomized animal model、OP of medicamentos animal model、OP of deficiency animal model and Parathyroid nephrectomy causing osteoporosis animal model etc.TCM prevent and treat osteoporosis begining with nourishing kidney.Many traditional Chinese medicine in prevention and treatment of the primary osteoporosis have obvious effect,such as barrenwort,psoralea corylifolia,drynaria fortunei,morinda officinalis how,dodder,common cnidium fruit,etc.Compared with single herb,complex prescription can develop more drug effect.Modern scholars obtain considerable progress in experimental research on prevention and treatment of the primary osteoporosis.Prevention and treatment of osteoporosis by TCM achieve comprehensive effects,has less side effect,has broad prospect.