运动和静态门控心肌断层显像对轻症病毒性心肌炎的诊断价值

Diagnostic value of exercise stress-rest gated myocardial perfusion imaging in patients with mild virus myocarditis

目的:探讨99mTc-甲氧基异丁基异腈(MIBI)门控心肌断层显像在诊断轻症病毒性心肌炎(VMC)中的应用价值。方法:用双探头多功能SPECT仪,对轻症VMC组68例和正常对照组34例进行运动-静息心肌灌注断层显像。结果:VMC组68例中门控心肌断层显像异常者56例,阳性率为82.35%;正常对照组34例心肌显像均未显示异常;2组间比较差异有统计学意义(χ2=62.09,P<0.01)。心肌显像异常者56例中,固定性缺损32例(57.14%),可逆性缺损4例(7.14%),混合性缺损8例(14.29%),反向再分布12例(21.43%);单灶性损害16例(28.57%),多灶性损害40例(71.43%)。结论:运动-静息门控心肌断层显像对轻症急性VMC患者的诊断有较大的临床实用价值。

Objective：To assess the value of exercise stress-rest gated myocardial perfusion imaging in the diagnosis of mild acute viral myocarditis（VMC）.Method：Exercise stress-rest 99mTc-MIBI gated myocardial SPECT imaging were performed in 68 patients with VMC and 34 cases of normal control.Result：Among 68 acute VMC patients,56 cases were showed as abnormal imaging with SPECT.The positive rate is 82.35%.And no abnormal imaging was detected in 34 cases of normal control.There was significant difference between two groups（χ2=62.09,P0.01）.Among 56 cases of abnormal SPECT imaging,there were 32 cases of fixed defects（57.14%）,4 cases of reversible defects（7.14%）,8 cases of mixed defects（14.29%）,12 cases of reverse redistribution（21.43%）,16 cases of single-focal lesion（28.57%）,40 cases of multi-focal lesions（71.43%）.Conclusion：Exercise stress-rest gated myocardial perfusion imaging has important clinical practical value in diagnosis of mild acute VMC.