格林-巴利综合征患者血清中髓鞘脂自身抗体水平的测定

Serum level of anti myelin sheath antibody in patients with Guillain Barre syndrome

应用免疫学方法检测了格林巴利综合征（ＧＢＳ） 病人和正常对照组各３０ 例的血清中髓鞘脂自身抗体含量， 并进行了动态观察。结果显示， ＧＢＳ病人血清中髓鞘脂自身抗体水平明显高于正常对照组（Ｐ＜ ００１）。ＧＢＳ患者髓鞘脂自身抗体出现的阳性率为２０％ 。动态观察发现， ＧＢＳ患者血清中髓鞘脂自身抗体水平的下降与临床症状的改善相一致。

To determine the serum anti myelin sheath antibody in 30 patients with Guillain Barre syndrome and 30 healthy subjects.A dynamic observation was performed in 5 patients with GBS.The result showed that the serum antimyelin sheath antibody increased signiflcantly in patients with GBS,compared with normal control( P <0 01).The positive rate of serum antimyelin sheath antibody titers in GBS patients was 20%,dynamic observation shows that the decrease of serum anti myelin sheath antibody is correlated with clinical symptomatic improvement.