沙美特罗／丙酸氟替卡松与温针灸对慢性阻塞性肺疾病稳定期肺功能及临床疗效影响的比较研究

Comparative research on affections of lung function and clinical curative by treatments of salmeterol/ fluticasone propionate and warm needing method on treating stationary chronic obstructive pulmonary disease

目的研究沙美特罗／丙酸氟替卡松与温针灸对慢性阻塞性肺疾病（COPD）稳定期肺功能的影响，观察其临床疗效和对临床症状改善的作用。方法将63例人选病例按照随机数字表分为沙美特罗／丙酸氟替卡松组和温针灸组各31例和32例，除去研究过程中的脱落病例，最终两组各完成30例和29例，按设计的治疗方案进行治疗，观察两组病例治疗后的第1秒用力呼气容积（FEV1）等肺功能改变、临床症状的评分和呼吸等生命质量的评价，进行组间和组内的比较。结果两组均有效的改善了FEV。1、FEV1／FVC、FEV1占预计值％等肺功能（P〈O．05或P〈0．01），提高了生活质量，沙美特罗／丙酸氟替卡松对缓解呼吸道症状快捷有效，温针灸对患者寒热等全身症状作用持久有效。两组的临床显效率、总体有效率各为40．。O％、86．67％和17．24％、86．21％，两者总有效率相当（P〉0．05），但沙美特罗／丙酸氟替卡松组具有良好的临床显效率（P〈O．05）。结论沙美特罗／丙酸氟替卡松和温针灸均能起到改善COPD稳定期患者肺功能的作用，沙美特罗／丙酸氟替卡松的作用快捷，而温针灸的作用持久。

Objective To research the affection of lung function by seretide and warm needing method to stationary chronic obstructive pulmonary disease （COPD） and observe the clinical curative and the effect on improve the clinical symptoms. Methods 63 cases were divided into a seretide group with 31 cases and a warm needing group with 32 cases according to the random number table and finished 30 cases and 29 cases respectively after removed off cases. Observed changes of lung functions as FEV1 , evaluated the life quality,and scores of clinical symptoms and did comparisons among and in groups after treated by designed plan. Results Lung functions as FEV1, FEV1/FVC, FEV1 0~ pred were both improved in two groups（ P 〈0.05 or P〈0.01）, increased the life quality seretide released respiratory symptoms swiftly and effectively and warm needing was effect to whole symptoms as warm and cold. The clinical excellent rate was 40.00%, 17.24G and the total effective rate was 86.67%,86.21% respectively and the tolal effective rate was fairly（ P 〉0.05）, but seretide group had a better clinical excellent rate（ P 〈0.05）. Conclusions Both seretide and warm needing were effect to improve the lung function of patients with stationary COPD and the effect of seretide was swiftly and warm needing was lasting.