苦皮藤中酚性成分抗羟自由基活性研究

THE SCAVENGING EFFECT OF PHENOLIC COMPOUNDS FROM C.ANGULATUS MAX.ON HYDROXYL FREE RADICALS

从苦皮藤中分离出四个酚性成分 :( +)儿茶素 ( 1) ,(— ) -表儿茶素 ( 2 ) ,3,4 ,5-三甲氧基 -苯 - 1- O- β- D-葡萄糖甙 ( 3)和 3,7,4 -三羟基 - 3 -甲氧基黄烷 - 5- O- β- D-葡萄糖甙 ( 4 )。其中 ( 4 )为新化合物。用电子自旋共振技术 ( ESR)研究了它们对羟自由基即(· OH)的清除作用。

WT5BZ]Four phenolic compounds:(+)catechin,( ) epicatechin,2,4,6 trimethoxy 1 O β D glycoside and 3,7,4 trihydroxy 3 methoxy flavan 5 O β D glycoside(new)have been isolated from Celastrus angulatus Max.Their scavenging effect on Hydroxyl free radicals have been studied by ESR technique with DMPO as spin trap.