纳洛酮治疗乙醇中毒患者的临床效果研究

Clinical study on the outcome of Naloxone treating alcoholism

目的研究纳洛酮治疗急性乙醇中毒的临床效果。方法回顾性分析我院2007年6月至2008年6月之间收治的急性乙醇中毒患者50例,所有患者给予静脉通道补液,并针对急性乙醇中毒的临床表现分期分别给予患者采取不同的纳洛酮治疗模式。结果所有患者治疗后意识逐渐.恢复,呼吸恢复正常,血压逐渐回升至正常,病情在3～12h症状消失,完全清醒,可稳步行走,纳洛酮组治愈率为100%。结论纳洛酮在临床急性乙醇中毒急救中具有作用快,治疗简便,疗效确切的特点,从而易于临床上的广泛应用。

Objective To study the clinical efficacy of Naloxone treating chronic alcoholism.Methods We made a retrospective analysis on 50 patients with chronic alcoholism who were treated in our hospital during the period from June 2007 to June 2008,all of them were given intravenous injections,naloxone therapy was adopted based on the differences of patients′ clinical siuation.Results All the 50 patients began to breathe normally, their consciousness was returned gradually,and their blood pressure returned to normal value,all the 50 patients returned consciousness absolutely with steady steps,they remained symptom-free in 3 to 12 h,the cure rate of naloxone therapy was 100%.Conclusion Naloxone proves an effective and precise therapy treating alcoholism with the features of briefness and convenience,so it can be adopted in the clinical treatment generally.