社区获得性肺炎合并脓毒症患者血清降钙素原和血糖监测的临床价值

The clinical value of serum procalcitonin and blood glucose in community-acquired pneumonia with sepsis

目的研究社区获得性肺炎(CAP)合并脓毒症患者血清降钙素原(PCT)和血糖的水平及其相关性。方法收集CAP患者96例,其中合并脓毒症46例,非脓毒症50例,选择同期体检人群30例为对照组。PCT检测用双抗体夹心免疫荧光法,血糖检测采用葡萄糖氧化酶法。结果 CAP合并脓毒症组PCT和血糖水平均明显高于非脓毒症组和对照组(P<0.05),且两者呈正相关(P<0.05)。随病情加重,其相关性越密切,Pearson相关系数分别为0.474、0.693和0.911。结论联合监测PCT和血糖对判断肺炎合并脓毒症病情严重程度具有一定的临床意义。

Objective To measure the level of serum procalcitonin（PCT） and blood glucose in community-acquired pneumonia with sepsis,to investigate their correlation and to evaluate the clinical value.Method 96 patients diagnosed as pneumonia were divided into CAP with sepsis group（n=46） and non-sepsis group（n=50）.30 cases of healthy people were selected as the control group.Result The level of serum PCT and blood glucose in sepsis group was significantly higher than the non-sepsis group and the healthy group（P0.05）.The levels of serum PCT and blood glucose were positive correlated.Pearson correlation coefficient was gradually increased.Conclusion The correlation of PCT and blood glucose increased with the severity of sepsis.The PCT and blood glucose could be used in the diagnosis of the severity of pneumonia with sepsis.