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内镜下经单鼻孔蝶窦入路切除垂体腺瘤的临床研究 被引量:3

Clinical study of pituitary adenoma resection through endoscopic endonasal transsphenoidal approach
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摘要 目的探讨神经内镜下经单鼻孔蝶窦入路在垂体腺瘤切除术中的临床应用。方法回顾性分析47例内镜下经单鼻孔蝶窦入路治疗垂体腺瘤患者的临床资料及手术方法,观察其疗效及并发症。结果肿瘤全切除39例(82.9%),次全切除6例(12.8%),部分切除2例(4.3%)。术后并发症有暂时性尿崩症11例,脑脊液鼻漏3例,术后鼻腔出血2例,颅内感染1例。无死亡病例。术后随访6~24个月,临床症状多有不同程度改善;术后内分泌学复查,25例激素水平降至正常,无肿瘤复发。结论内镜下经单鼻孔蝶窦入路切除垂体腺瘤具有创伤小、并发症少、患者恢复快等优点,是治疗垂体腺瘤的一种安全、有效的方法。 [Objective] To explore the clinical application of surgery for pituitary adenoma via endoscopic endonasal transsphenoidal approach.[Methods] The clinical data and surgical methods of 47 patients with pituitary adenomas,who were treated by endoscopic endonasal transsphenoidal surgery,were analyzed respectively to observe the effects and complications.[Results] The tumors were totally removed in 39 cases(82.9%),subtotally removed in 6 cases(12.8%) and partly removed in 2 cases(4.3%).Postoperative complications included temporary diabetes insipidus in 11 cases,cerebrospinal fluid leakage in 3 cases,2 cases of postoperative nasal hemorrhage and intracranial infection in 1 case.There was no surgical death.With 6~24 months' follow-up,The clinical symptoms in all patients were improved in varying degrees;The hormone levels in 25 cases decreased to normal postoperatively and without recurrent case.[Conclusion] It is considered that Endoscopic endonasal transsphenoidal surgery for pituitary adenoma,which has many advantages,such as minimal invasion,less complications and quick recovery of patients,is a safe and effective method for the treatment of pituitary adenomas.
出处 《中国内镜杂志》 CSCD 北大核心 2011年第8期824-827,共4页 China Journal of Endoscopy
关键词 垂体腺瘤 经鼻蝶入路 神经内镜 pituitary adenoma endonasal transsphenoidal approach endoscope
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