原发性肾病综合征中医证候荟萃分析

Meta-analysis of primary nephritic syndrome from a perspective of Chinese Medicine

目的研究原发性肾病综合征的中医证候分布,总结其主要的证候类型。方法通过计算机检索国内1997-2010年关于中医药治疗原发性肾病综合征的文献,运用随机对照试验表对文献进行评估,采用JADAD治疗评分表对文献进行评价,将符合标准的文献运用加权百分率法进行荟萃分析。结果共有9篇文献入选本研究,得到701例病人15种证型,其中主要的证型为脾肾阳虚型(29.5%)、肝肾阴虚型(16.7%)、阴虚湿热型(13.8%)。结论脾肾阳虚、肝肾阴虚、阴虚湿热为原发性肾病综合征的主要证型。

Objective To study the occurrence of primary nephritic syndrome （PNS） and determine the major causes of the syndrome.Methods All reviewed literatures were assessed using the JADAD quality scale.A total of 9 articles on Chinese Medicine for PNS were retrieved and analyzed for the syndrome occurrence.Results A total of 701 cases were analyzed and 15 patterns of syndrome were observed.The top three patterns were spleen-kidney yang deficiency （29.5%）,liver-kidney yin deficiency （16.7%）,and yin deficiency damp-heat （13.8%）.Conclusion Primary patterns of PNS are spleen-kidney yang deficiency and liver-kidney yin deficiency and yin deficiency damp-heat.