马齿苋提取液冷喷治疗面部敏感性皮肤的研究

Study on the Hypothermia Atomization of Portulacaeracea Extracting Solution in Treating Facial Sensitive Skin

目的:观察新鲜马齿苋提取物冷喷治疗对面部敏感性皮肤患者的临床疗效、不良反应及对皮肤屏障功能的修复作用。方法:新鲜马齿苋提取液用蒸馏水稀释10倍,用于面部敏感性皮肤患者的冷喷治疗,观察患者的主观症状、客观症状积分,用皮肤多功能测试仪检测治疗前后经皮水分丢失(trans-epidermal water lose,TEWL),以蒸馏水冷喷组为对照。结果:新鲜马齿苋提取液冷喷治疗面部敏感性皮肤有效率为85%,显著高于蒸馏水冷喷对照组的55%;新鲜马齿苋提取液冷喷治疗面部敏感性皮肤,与蒸馏水冷喷对照组比较,在治疗10天和20天时,均能显著改善患者的主客观症状及皮肤屏障功能,不但起效快,而且疗效持久;新鲜马齿苋提取液冷喷治疗面部敏感性皮肤与蒸馏水冷喷对照组比较,不良反应发生率无明显差异性。结论:新鲜马齿苋提取液冷喷治疗面部敏感性皮肤,有较好的临床疗效和较低的副反应,适合进一步开发成专业治疗面部敏感性皮肤的低温喷雾剂。

Objective：To observe the clinical curative effect,bad reaction and skin barrier functional repairing of hypothermia atomization of the fresh Portulacaeracea extracting solution in treating facial sensitive skin.Methods：The fresh Portulacaeracea extracting solution was diluted by distilled water for ten times,using to treat facial sensitive skin through hypothermia atomization.We observed the subjective symptom,recorded the objective symptom score and detected trans-epidermal water lose before and after treatment.The hypothermia atomization of distilled water was used as the control.Results：The availability of hypothermia atomization of the fresh Portulacaeracea extracting solution in treating facial sensitive skin was 85%,which was significantly higher than that of the 55% availability of distilled water treatment groups.And compared with distilled water treatment groups in treatment on the 10th and 20th day,the fresh Portulacaeracea extracting solution could notablely improve the patients＇ subjective symptom and skin barrier functional repairing with quick and duration curative effect.While there was no significant difference of the bad reaction between the fresh Portulacaeracea extracting solution and distilled water.Conclusion：When using the fresh Portulacaeracea extracting solution to treat facial sensitive skin,there was good clinical curative effect and little bad reaction,so it was suitable to be developed into the hypothermia nebula for professional treating facial sensitive skin.