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罗哌卡因与布比卡因用于腰硬联合麻醉剖宫产的临床效果对比 被引量:26

Clinical Efficacy Comparion of Ropivacaine and Levobupivacaine for Combined Spinal-Epidural Anesthesia(CSEA) on Caesarean Section
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摘要 目的:探讨罗哌卡因与布比卡因用于腰硬联合麻醉剖宫产的临床效果。方法:采用随机双盲对照试验设计,将60例择期行腰硬膜联合麻醉剖宫产产妇按照1:1的比例随机分为罗哌卡因组和布比卡因组。罗哌卡因组:0.75%罗哌卡因2ml,布比卡因组:0.75%布比卡因2ml用脑脊液稀释到3ml注药2ml。结果:两组最高感觉阻滞平面、到达最高阻滞平面时间、感觉恢复时间、麻醉效果无显著性差异(P>0.05),罗哌卡因组感觉起效时间、运动阻滞起效时间明显晚于布比卡因组(P<0.05),运动恢复时间明显快于布比卡因组(P<0.05);罗哌卡因组低血压、心动过缓、恶心呕吐和头晕均少于布比卡因组,其中低血压有显著性差异(P<0.05)。结论:与布比卡因比较,罗哌卡因麻醉效能相似,但运动恢复更快,利于早期下床活动,且不良反应少,更适用于腰硬联合麻醉剖宫产。 Objective:To investigation the of ropivacaine and levobupivacaine for combined spinal-epidural anesthesia(CSEA) on caesarean section.Methods: Use randomized double-blind controlled trial design,sixty primiparae sehedualed for caesarean section were divided into ropivacaine group and bupivacaine group in 1:t proportion.Ropivacaine group: 0.75% ropivacaine 2ml, bupivacamc group: 0.75% bupivacaine 2ml was diluted to 3ml with cerebrospinal fluid,injection 2ml.Results: There were no significant difference on the highest sensory block plane, reach the maximum block plane time, sensory recovery time, anesthesia effect m the two groups (P〉 0.05), sensory onset time, motor block onset time of ropivacaine group was significantly later than that of bupivacaine group (P 〈 0.05 ). motor recovery was significantly faster than the bupivacaine group (P〈0.05); the cases of hypotension, bradycardia, nausea, vomiting and dizziness in ropivacaine group were less than the bupivacaine group, the hypotension cases has significantly differences (P〈 0.05) Conclusion: Compared with bupivacaine, ropivacaine anesthesia has similar effccts, but it has faster motor recovery time, conducive to early ambulation, and has fewer adverse reactions, is more suitable for epidural anesthesia on cesarean section.
作者 谢伟
出处 《中国医药导刊》 2011年第10期1764-1765,共2页 Chinese Journal of Medicinal Guide
关键词 罗哌卡因 布比卡因 腰-硬联合麻醉 剖宫产 Ropivacaine Bupivacaine CSEA Cesarean section
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