胃癌新TNM分期法的应用价值及预后意义

THE APPLICATION VALUE AND PROGNOSTIC SIGNIFICANCE OF THE NEW TNM STAGING SYSTEM FOR GASTRIC CANCER

采用国际统一胃癌新ＴＮＭ分期法对１１７５例胃癌切除术病例进行了分期、随访和统计，并对新分期法判断预后的价值进行了相应的统计学检验。结果：Ⅰａ、Ⅰｂ、Ⅱ、Ⅲａ、Ⅲｂ和Ⅳ期的５年生存率分别为１００％、８４％、６５％、４３％、２５％及１３％，且同期内各亚组间的生存率十分接近；对新分期法与预后的关系作相关与回。归分析，结果显示相关系数ｒ＝０．９９０（Ｐ＜０．０００５），回归系数ｂ＝０．１３４５（Ｐ＜０．０００５）。由此表明，胃癌新ＴＮＭ分期法与预后具有统计学的一致性，证实了新分期法的应用合理性及反映预后的准确性。

In this report, 1175 cases of resected gastric cancer were staged, followed up and statisti cally calculated by using the international unifying new TNM staging system for gastric cancer. The prognostic value of the new TNM staging system was also tested with relevant statistics. The results showed that: (1) the 5-year survival rates of Ⅰa, Ⅰb, Ⅱ,Ⅲa, Ⅲb and Ⅳ were 100%,84%,65%,43%,25% and 13% respectively；(2) the 5-year survival rates of the subgroups within same stage were quite;(3) the analyses of correlation and regression between the new staging and the prognosis provided that correlation coefficient r equals to -0. 990 (P＜0. 0005), and regression coefficient b equals to-0. 1345 (P＜0. 0005). These results indicate that there is statistical identity between the new TNM staging for gastric cancer and the prognosis, and certify the rationality for the new staging in application and its ac curacy to reflect the prognosis.