顺尔宁联合舒利迭气雾剂吸入治疗儿童支气管哮喘疗效观察

Observation on the curative effect of Singulair combined with inhalation of seretide evohaler in treatment of children with bronchial asthma

目的:观察顺尔宁联合舒利迭气雾剂吸入治疗支气管哮喘的疗效,为制定支气管哮喘的治疗方案提供参考依据。方法:120例支气管哮喘患儿随机分为对照组和治疗组,每组各60例,两组均给予补液、解痉、抗炎、吸氧等常规治疗。对照组在常规治疗基础上给予布地奈德气雾剂吸入,而治疗组给予顺尔宁,1次/日,睡前温开水送服,同时联合舒利迭气雾剂吸入治疗,对两组的疗效进行分析。结果:对照组总有效率为76.7%,治疗组总有效率为95.0%,两组总有效率比较差异有统计学意义(χ2=8.254,P=0.0062)。与治疗前比较,两组患儿治疗后FEVl占预计值百分率,PEF占预计值百分率明显增加,且治疗组改善更为明显(P<0.05)。结论:顺尔宁联合舒利迭气雾剂吸入治疗支气管哮喘具有协同作用,疗效确切,能明显改善患儿肺功能,值得临床推广应用。

Objective：To observe the curative effect of Singulair combined with inhalation of seretide evohaler in treatment of children with bronchial asthma,provide a reference for making therapeutic scheme for bronchial asthma.Methods：120 children with bronchial asthma were randomly divided into control group and treatment group,60 children in each group,all the children in the two groups were treated with conventional treatment,such as fluid infusion,antispasmodic,anti-inflammatory and oxygen inhalation.The children in control group were treated with inhalation of budesonide on the basis of conventional treatment;while the children in treatment group were treated with oral administration of Singulair（once a day） combined with inhalation of seretide evohaler;the curative effects in the two groups were analyzed.Results：The total effective rates in control group and treatment group were 76.7% and 95.0%,respectively,there was significant difference between the two groups（χ2=8.254,P=0.0062）.After treatment,FEVI% and PEF% in the two groups increased significantly,especially in treatment group（P0.05）.Conclusion：Singulair combined with inhalation of seretide evohaler has a synergistic effect for treatment of children with bronchial asthma,the curative effect is confirmed,the method can improve the pulmonary function of children,which is worthy to be popularized in clinic.