益气通腑法治疗慢性阻塞性肺疾病急性加重患者临床研究

Clinical Research of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD) Treated by Tonifying Qi and Unblocking Fu

目的:观察益气通腑法对慢性阻塞性肺疾病急性加重(AECOPD)患者的临床疗效。方法:将60例慢性阻塞性肺疾病急性发作患者随机分为治疗组和对照组,两组均常规采用西医治疗,治疗组加用益气通腑方药,疗程为7 d;观察治疗前后主要临床症状积分变化及肺功能等的变化。结果:治疗组能显著改善患者主要临床症状,呼吸频率、心率、动脉氧分压、动脉二氧化碳分压、FEV1.0、PEF均明显改善,与对照组比较,差异有统计学意义(P<0.01,P<0.05)。结论:益气通腑法能显著改善患者临床症状,有效改善AECOPD患者肠道功能,提高呼吸动力,改善肺通气功能。

Objective：To observe the clinical effect of Acute Exacerbation of Chronic Obstructive Pulmonary Disease（AECOPD） treated by tonifying Qi and unblocking Fu.Methods：60 cases of AECOPD were divided randomly into experimental group（30 cases） and control group（30 cases）,both the groups were given routine western medicine treatment,otherwise,the experimental group took added Qi-tonifying and Fu-unblocking prescriptions.The course of treatment is 7 days.The changes of the major clinical symptoms scores and the pulmonary function before and after treatment were observed.Results：The major symptoms of 30 cases in experimental group were significantly advanced.The breathing rate,heart rate,arterial oxygen pressure,partial pressure of carbon dioxide in artery,FEV1.0 and PEF were improved obviously,in comparison with those of control group,there were significances in statistics（P〈0.01,P〈0.05）.Conclusions：Tonifying Qi and unblocking Fu can improve the clinical symptoms obviously,better the bowel function of COPD patients,raise the respiratory drive and polish up the pulmonary ventilation function.