小牛血去蛋白眼用凝胶治疗干眼的临床分析

Clinical analysis of deproteinized calfblood extract eye gel for treatment of dry eye

目的:通过观察干眼症患者使用小牛血去蛋白眼用凝胶(速高捷)前后,患者的主观症状、干眼实验室检查结果的变化,评估小牛血去蛋白眼用凝胶干眼症的疗效。方法:选择干眼症患者22例43眼,予以小牛血去蛋白眼用凝胶滴眼,3次/d。观察就诊当天、用药1,2wk;1mo患者主观症状:干涩感、异物感、烧灼感、视疲劳、眼红、疼痛、畏光、流泪;干眼实验室检查:荧光素染色、泪膜破裂时间、SchirmerⅠ试验。结果:用药1mo后,患者的干涩感、异物感、烧灼感、视疲劳、眼红、疼痛、畏光、流泪等主观症状的分级与用药前有显著差异(P<0.01),8种主观症状明显缓解;用药后患者的荧光素染色,BUT及SⅠt值与用药前有显著差异(P<0.01)。结论:小牛血去蛋白眼用凝胶对干眼症治疗有效。

AIM：To evaluate the efficacy of deproteinized calfblood extract eye gel for dry eye by observing changes in the patient＇s subjective symptoms and laboratory test results of dry eye before and after treatment.METHODS：Totally 22 selected cases of 43 dry eyes were treated with deproteinized calfblood extract eye gel 3 times/d.Patients were observed with subjective symptoms：dryness,foreign body sensation,burning sensation,visual fatigue,redness,pain,photophobia,lacrimation;and dry eye laboratory tests：fluorescein staining,tear film break-up time（BUT）,SchirmerⅠtest（SⅠt） on the day of treatment and 1 week,2 weeks,1 month after medication.RESULTS：One month after medication,the patient＇s subjective symptoms gradings were significantly different with those before treatment（P0.01）,the 8 subjective symptoms were visibly relieved;after treatment,the patient＇s fluorescein staining,BUT and SⅠt values were significantly different with those before treatment（P0.01）.CONCLUSION：Deproteinized calfblood extract eye gel is effective for treatment of dry eye.