退行性腰椎侧凸与骨质疏松症的关系探讨

Relation Investigation of Degenerative Lumbar Scoliosis and Osteoporosis

目的探讨退行性腰椎侧凸(degenerative lumbar scoliosis,DLS)与骨质疏松症(osteoporosis,OP)两者之间的关系。方法选取2006年6月～2010年6月来我院就诊的DLS患者58例及对照组(非腰椎侧凸的腰痛患者)58例,对DLS组Cobbs’角进行测量,并采用双能X线吸收法检测两组患者腰椎(L2～L4)、股骨颈、股骨粗隆和Wards’三角区骨密度T值,分析患者年龄、Cobbs’角与骨密度T值的相关性。结果 DLS组平均骨密度T值为-2.7±1.8,合并OP 45例,发病率为77.59%;对照组平均骨密度T值为-1.3±1.0,合并OP 8例,发病率为13.79%,两组比较有显著性差异(P<0.05)。相关分析显示,DLS患者T值与年龄呈正相关(r=0.318,P<0.01),与侧凸Cobbs’角无关。结论 OP是DLS发病的危险因素,同时年龄越大OP程度越重,但与DLS进展程度无关。临床DLS治疗时要考虑到OP的影响。

Objective To investigate the correlation between degenerative lumbar scoliosis （DLS） and osteoporosis（OP）. Methods From Jun 2006 to Jun 2010,58 patients with DIS and 58 patients with no DIS （control group）were choosen. The bone density of lumbar,femoral neck,troehanter,Ward＇s triangle regions in both groups were measured with dual-energy X-ray absorptiometry. The T-scores of different ages and Cobb＇s angles were observed and their correlations was analyzed. Results In DIS group,the average T-score was -2.7 ±1.8,45 cases combined with OP,the incidence was 77.59%;In control group,the average T-score was -1.3± 1.0,8 cases combined with OP,the incidence was 13.79%. There were significant difference between DLS group and control group （P〈0.05）. The T-score existed a positive correlation with age,and no corelation with Cobb＇s angle. Conclusion OP is a risk factor for DLS, and the severity of OP has no correlation with the progress of DLS,but increases with the increasing of age. The influence of OP should be considered for DIS treatment.