摘要
目的探讨18氟标记的脱氧葡萄糖(18F-FDG)PET/CT显像对淋巴瘤疗效评价的意义。方法回顾分析我院64例淋巴瘤治疗后18F-FDG PET/CT显像结果,与治疗后单纯CT结果进行对比分析,最终结果经病理和临床随访证实。结果最终共发现病灶219处,其中恶性208处,良性11处。18F-FDG PET/CT评价淋巴瘤治疗效果的灵敏度、特异性、准确性分别为99.52%(207/208)、90.91%(10/11)及99.09%(217/219),均明显优于单纯CT检查(P<0.05)。结论 18F-FDG PET/CT在淋巴瘤疗效评价方面明显优于CT,可为临床选择治疗方案提供早期客观的科学依据,是淋巴瘤疗效监测的有效手段。
Objective To evaluate the value of ^18F-fluorodeoxyglucose （FDG） PET/CT imaging in evaluation of response to treatment in lymphoma. Methods Sixty-four post-treatment patients with lymphoma were studied retrospectively. PET/CT images after therapy were compared with CT posttherapy results. The final diagnosis was based on pathology or clinical follow-ups. Results A total of 208 malignant lesions and 11 benign lesions were found in 64 patients in the study. The sensitivity, specificity and accuracy of ^18F-FDG PET/CT were 99.52% （207/208）, 90.91% （10/11） and 99.09% （217/219）, respectively. The difference was significant between PET/CT image and CT alone in sensitivity, specificity and accuracy （P 〈 0.05）. Conclusion ^18F-FDG PET/CT is better than CT images in the evaluation of response to treatment in lymphoma and ^18F-FDG PET/CT examination will become one of the effective technizues in the future.
出处
《临床误诊误治》
2012年第1期71-74,共4页
Clinical Misdiagnosis & Mistherapy
基金
河北省普通高等学校强势特色学科肿瘤学组(冀教高2005[52])
河北省卫生厅"医学科学研究重点课题计划"项目(20100437)
