藏药樱草杜鹃中的酚类成分

Phenols in Rhododendron primulaeflorum Bur.et Franch

目的研究藏药樱草杜鹃(Rhododendron primulaeflorum Bur.et Franch.)的嫩枝和嫩叶中的酚类成分。方法利用色谱方法分离和纯化化合物,并通过光谱方法及理化性质鉴定其结构。结果从樱草杜鹃中分离得到8个酚类化合物,分别鉴定为cannabichromeorcinic acid(1)、苔色酸甲酯(2)、苔色酸(3)、苔黑酚-O-β-D-吡喃葡萄糖苷(4)、2,6-二甲氧基-4-羟基苯酚-1-O-β-D-吡喃葡萄糖苷(5)、lyoniside(6)、4,6-二羟基-2-O-(β-D-吡喃葡萄糖苷)苯乙酮(7)、3,5-二羟基-4-O-(β-D-吡喃葡萄糖苷)苯乙酮(8)。结论除化合物2外,其余化合物均为首次从该植物中分离得到。

OBJECTIVE To study the phenols in the young branches and leaves of Rhododendron primulaeflorum Bur. et Franch. METHODS The constituents were separated and purified by chromatographic methods, and their structures were elucidated by spec- troscopic methods and chemical analyses. RESULTS Eight known phenol compounds, cannabichromeorcinie acid（ 1 ） , methylorselli- nate（ 2 ）, orsellinie acid （ 3 ）, oreinol-O-β-D-glucopyranoside （ 4 ）, 2, 6-dimethoxy-4-hydroxyphenyl-1 -O-β-D-glucopyranoside （ 5 ）, lyo- niside （ 6 ）, 4, 6-dihydroxy-2-0- （β-O-glucopyran-osyl ） acetophenone （ 7 ） and 3, 5 -dihydroxy-4-O- （β-O-glucopyranosyl） acetophenone （ 8 ） were isolated from the plant. CONCLUSION All of the compounds except compound 2 were isolated from this plant for the first time.