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改良VAD方案治疗老年多发性骨髓瘤13例 被引量:14

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摘要 多发性骨髓瘤(MM)是一种浆细胞异常增生的一类恶性血液疾病,好发于中老年人,约占血液系统肿瘤的10%-15%,临床上主要表现为浆细胞的恶性克隆增生、M蛋白血症、感染等。目前主要治疗方法是化疗和干细胞移植^[1]。蛋白酶体抑制剂硼替佐米(PS341)是一种新型的抗MM药物,但由于价格较贵限制了其临床应用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第2期365-366,共2页 Chinese Journal of Gerontology
基金 广西壮族自治区卫生厅资助项目(Z2011431)
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参考文献5

  • 1Koren J,Spicka I,Straub J,et al.Retrospective analysis of the results ofhigh-dose chemotherapy with the support of autologous blood stem cells inpatients with multiple myeloma.The experience of a single central[J].Prague Med Rep,2010;111(3):207-18.
  • 2Barlogie B,Kyle RA,Anderson KC,et al.Standard chemotherapy com-pared with high-dose chemoradiotherapy for multiple myeloma:final re-sults of phase III US Intergroup Trial S9321[J].J Clin Oncol,2006;24(6):929-36.
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  • 4陈世伦.重视多发性骨髓瘤的规范化治疗[J].中华内科杂志,2005,44(2):81-82. 被引量:11
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二级参考文献10

  • 1Barlogie B, Jagannath S, Desikan KR, et al. Total therapy with tandem transplants for newly diagnosed multiple myeloma. Blood,1999.93:55-65.
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  • 10Zangari M, Barlogie B, Thertulien R, et al. Thalidomide and deep vein thrombosis in multiple myeloma: risk factors and effect on survival. Chin Lymphoma, 2003,4:32-35.

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引证文献14

二级引证文献77

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