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右美托嘧啶用于上肢手术术后镇痛效果观察 被引量:6

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摘要 目的 采用随机、双盲的方法观察右美托嘧啶通过术后肌间沟置管持续泵注给药用于肱骨骨折内固定术后镇痛的效果。方法 选择择期行肱骨骨折内固定术术后镇痛的患者60例,随机分为0.2%罗哌卡因+右美托嘧啶100μg组(DEX组),0.2%罗哌卡因+芬太尼0.3mg对照组(FEN组)。每组药液总量均为100mL,术后镇痛通过肌间沟置管持续泵注给药,负荷量2mL,每小时持续泵注量2mL,PCA剂量2mL,持续观察24h,于术后第1、2、4、8、16、24小时观察记录患者的心率、血压、脉搏氧饱和度、非甾体镇痛药的需求、其他不良反应、VAS评分、PCA总次数、有效按压次数及两者之比。结果 各组间心率、血压、脉搏氧饱和度无明显差异(P>0.05)。而右美托嘧啶组VAS评分明显低于其余两组。结论 右美托嘧啶用于神经丛术后镇痛效果明显优于芬太尼,且无不良反应。
出处 《中国医药科学》 2012年第1期124-125,共2页 China Medicine And Pharmacy
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