高危人群梅毒检测结果分析

The Results of Syphilis Testing of High-risk Groups

目的:了解陕西省汉中市略阳县高危人群梅毒感染情况,为制定相应的干预措施和实验室检测策略提供依据。方法:对2010年组织到我院体检的高危人群采用梅毒螺旋体ELISA试验(TP-ELISA)方法进行检测,阳性结果用梅毒螺旋体明胶凝集试验(TPPA)进行确认。结果:2010年共129份血清样本(上半年61份,下半年68份),ELISA法共检出阳性16例,阳性率为12.40%,有2例经TPPA法确诊为阴性,特异性为89.15%。结论:本地区高危人群梅毒感染率高,实验室应该尽快制定相应的预防、检验和治疗策略,控制梅毒的性传播途径,降低梅毒感染带来的危害性;同时证明ELISA检测法特异性好,可作为高危人群梅毒感染的一种理想检测方法,但对ELISA阳性标本应做TPPA确认。

Objective：To find out the syphilis infection situation of high-risk groups of lueyang,to provide the basis of the formulations for Interventions and the detection strategy for Laboratory. Methods：Againsting the High-risk groups who came to the hospital in 2010,tests will take Enzyme-Linked Immunosorbent Assay（ELISA） as the testing measures and positive results will be dealt with Treponema Pallidum Agglutination test（TPPA） for confirmation. Results：There are 129 serum samples this year（61 in the first half and 68 in the rest）.Among these serum samples,16 samples turned out to be positive under the measurement of ELISA.Among the16 ELISA positive samples,2 were confirmed negative,with specificity of 89.15%. Conclusions：ELISA testing measure has advantages in its better specificity,so it can be an ideal measurement for Syphilis infection and means a lot in controlling the spread of Syphilis by sex.A confirmative testing should be made to ELISA positive samples by TPPA though.