假酸浆中新的醉茄内酯类化合物(英文)

New Withanolides from Nicandra physaloides (Solanaceae)

从假酸浆(Nicandra physaloides)全草中分离得到12个化合物,其中两个为新的醉茄内酯类化合物,经波谱学方法将其结构鉴定为nicandrenone methyl ether(1)和26S-nicandrenone methyl ether(2);已知化合物为三个醉茄内酯,nicandrenone(3),Nic-7(4),nicaphysalin E(5),以及pinosylvin monomethylether(6),2S-pinocembrin(7),(1S,2R)-1,2-bis(4-hydroxy-3-methoxyphenyl)-1,3-propanediol(8),vanil-lin(9),indole-3-carboxylic acid(10),vanillic acid(11)和drummondol(12)。

Two new withanolides, named nicandrenone methyl ether （1）, 26Snicandrenone methyl ether （2）, together with ten known compounds were isolated from the whole plants of Nicandra physaloides （Solanaceae）. Their chemical structures were deduced on the basis of spectroscopic analysis. Ten known compounds were identified as nicandrenone （3）, Nic-7 （4）, nicaphysalin E （5）, pinosylvin monomethyl ether （6）, 2S-pinocembrin （7）, （1S, 2R）-1, 2-bis （4-hydroxy-3-methoxyphenyl）-1, 3-propanediol （8）, vanillin （9）, indole-3-carboxylic acid （10）, vanillic acid （11） and drummondol （12）.