腰椎间盘突出症与腰椎管狭窄症中西医病机研究进展

The research on the western-traditional chinese medicial pathogenesises of lumbar disc herniation and spinal stenosis

目的:对现代医学和传统医学腰椎间盘突出症和(或)腰椎管狭窄症主要机理的综述,望能为今后临床治疗提供参考。方法:查阅近10年来的相关文献,记录并总结所诉腰椎间盘突出症和(或)腰椎管狭窄症机理。结果:腰椎间盘突出症现代医学机理包括椎间盘退行性变、椎间盘基质成分的变化、细胞过度凋亡、生物力学改变、炎症因素等;腰椎管狭窄症则与压迫因素、血循环障碍因素和炎症介质刺激等有关。传统医学在脏腑、五行、运气理论、经络理论均有论述。结论:现代医学对于腰椎间盘突出症及腰椎管狭窄症的研究较多,但有重复倾向。现代传统医学对其研究,大多数研究仅停留在临床疗效观察阶段,机制的研究较少。

Objective:summary the main western-traditional chinese medicial pathogenesises of lumbar disc herniation and spinal stenosis,so as to probide a reference for future clinical treatment.Methods:access to the literatures on western-traditional chinese medicial pathogenesises of lumbar disc herniation and spinal stenosis about 10 years,record and summed up the pathogenesises.Results:in this research,western medicical believes that lumbar disc herniation because of the disc degeneration,composition of disc matrix changes,excessive apoptosis,biomechanical changes and inflammatory.Lumbar spinal stenosis relates to comression,blooding-disorder circulation and the stimulation of inflammatory mediators.The pathogenesises of the traditonal chinese medicine are discussed on the orgens,the five elements,the Yun-qi theory and meridian theory.Conclusions:the western medicial studies are more about the lumbar disc herniation and spinal stenosis,but tend to overlap,mordern traditional chinese medicial studies most stay on the observe of the medicine clinical efficacy,pathogenesis less.