成人急性腹泻患者血常规和C反应蛋白变化及意义

Change of blood routine parameters and C-reactive protein level and its significance in adult acute diarrhea

目的探讨成人急性腹泻患者红细胞压积(blood hematocrit,HCT)、WBC计数、中性粒细胞比率(percentage of neutrophils,NE%)和C反应蛋白(C-reactive protein,CRP)的变化及意义。方法 260例腹泻患者以脱水程度分为轻度脱水组189例、中度脱水组49例与重度脱水组22例,分别检测3组患者体温、HCT,WBC,NE%及CRP水平。结果重度脱水组HCT水平较轻、中度脱水组明显升高(P<0.05),中度脱水组较轻度脱水组明显升高(P<0.05);3组体温、WBC,NE%,CRP水平比较差异无统计学意义(P>0.05);3组患者中WBC>10×109,NE%>75%,CRP>10mg/L及HCT>49%的构成比比较差异均有统计学意义(P<0.05)。结论急性腹泻患者HCT水平变化对判断脱水程度有一定价值,WBC与CRP水平对指导临床用药有一定价值。

Objective To investigate the changes and significance of blood hematocrit（HCT）,white blood cells count（WBC）,percentage of neutrophils（NE%） and C-reactive protein（CRP） levels in patients with adult acute diarrhea.Methods A total of 260 patients were divided into mild dehydration group（n=189）,moderate dehydration group（n=49） and severe dehydration group（n=22）.All these three groups were detected the temperature,HCT,WBC,NE% and CRP levels.Results The HCT level was higher in severe dehydration group than that in the other two groups（P0.05）,and was higher in moderate group than that in mild group（P0.05）.There were no significant differences in temperature,WBC,NE% or CRP levels in three groups（P0.05）.There were significant differences in the constituent ratios in three group（P0.05） when WBC 10×109,NE% 75%,CRP 10 mg/L and HCT 49% respectively.Conclusion To monitor hematocrit level is helpful to assessing the degrees of dehydration.WBC and CRP level have value to the guidance of clinical medication.