老年重症肺炎50例临床治疗体会

The Experience of Therapy to the Old Patients with Severe Pneumonia

目的:探讨抗生素降阶梯疗法在治疗老年重症肺炎时的临床效果。方法:将我院2007年4月至2011年4月收治的50例老年重症肺炎患者按治疗方法分为两组,每组25例,一组为抗生素降阶梯疗法作为治疗组,另一组为常规抗生素治疗作为对照组,观察两组用药后的临床效果。结果:经过抗生素降阶梯治疗后患者疗效明显,有效例数为19例,有效率为76%,病死例数1例,病死率为4%;经过常规抗生素治疗后患者治疗有效例数为11例,有效率为44%,病死例数6例,病死率为24%。同时在患者加护住院时间、感染控制时间、总住院时间上治疗组均比对照组有明显降低,P<0.05具有显著差异。结论:抗生素降阶梯疗法在治疗老年重症肺炎时临床效果明显优于常规抗生素治疗,应予临床上推广。

Objective： To study the clinical effects de-escalation of antibiotic therapy in the treatment of old patients with severe pneumonia.Method： In our hospital from Apr.2007 to Apr.2011,50 elderly patients admitted with severe pneumonia were randomly divided into two groups,one is therapy group of de-escalation of antibiotics and the other is conventional antibiotic treatment group.After treatment,We observed the clinical results. Result： De-escalation after antibiotic treatment is effective in 19 patients after treatment,the effective rate was 76%,1 case died,mortality was 4%;after conventional antibiotic treatment,11 cases with effective treatment,efficiency was 44%;6 cases died,mortality was 24%.While length of stay in intensive care patients,infection control time,the total length of stay on the former than the latter are significantly lower P 0.05. Conclusion： De-escalation antibiotic therapy in the treatment of old patients with severe pneumonia clinically superior to conventional antibiotic treatment effect.