复发性阿弗他溃疡与外周血超氧化物歧化酶的相关性

Serum SOD levels in patients with recurrent Aphthous ulcer

目的 探讨复发性阿弗他溃疡（RAU）与外周血超氧化物歧化酶（SOD）的关系.方法 选取RAU患者112例（观察组,轻型RAU 33例、重型RAU 41例、疱疹样RAU 38例）,同期另择健康人30例作为对照组,检测比较两组对象外周血SOD水平.结果 观察组SOD水平明显低于对照组,差异有统计学意义（P＜0.05）.观察组中重型RAU患者SOD水平明显低于对照组轻型与疱疹样RAU患者,差异均有统计学意义（均P＜0.05）,轻型与疱疹样RAU患者SOD水平的差异无统计学意义（P ＞0.05）.结论 RAU与SOD水平密切相关,监测RAU患者外周SOD水平的变化对于诊断及治疗有着积极的意义.

Objective To investigate the serum superoxide dismutase（SOD） levels in patients with recurrent Aplqtnous ulcer （RAU）. Methods One hundred and twelve patients with RAU were enrolled in the study, including 33 cases of minor RAU （MiRAU）, 41 cases of major RAU（MaRAU） and 38 cases of herpetiform ulcer（HU）. Thirty healthy subjects served as control group. The serum SOD levels were detected and compared in both groups. Results The serum SOD levels of RAU group were signif- icantly lower than those of control group（P〈0.5）. The serum SOD levels of MaRAU cases were significantly lower than those of MiRAU and HU cases（P〈0.5） ; however, there were no statistical differences between MiRAU and HU cases（P 〉0.5）. Conclusion The serum SOD levels are closely correlated with RAU, and the measurement of serum SOD may be used for diagnosis and treatment of RAU.