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重症肌无力胸腺异常的影像学诊断(附120例临床分析) 被引量:1

Radiologic diagnosis of the thymus ahnormality in myasthenia gravis
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摘要 目的 :评价重症肌无力胸腺异常的影像学检查手段。方法 :对经手术病检证实的 1 2 0例重症肌无力伴胸腺异常患者的影像学改变与病理诊断进行对比研究。结果 :CT和 MRI诊断胸腺瘤、胸腺增生的灵敏度明显高于传统 X线检查 ( X线平片及体层摄影 ) ( P<0 .0 5) ,而 CT和 MRI之间无明显差别 ( P>0 .0 5) ;4种影像学检查方法诊断腺瘤、胸腺增生的病理符合率无显著差别 ( P>0 .0 5)。结论 :传统 X线检查诊断胸腺异常的价值较低 ,纵隔MRI和胸部 CT扫描诊断胸腺异常的价值相似 ,重症肌无力患者应常规进行胸部 CT检查。 Objective:To comparatively evaluate the imaging diagnostic methods used in thymus abnormalities associated with myasthenia gravis(MG).Methods:120 MG patients with thymus abnormalites were studied,all patients had been confirmed by pathologic examinations,Retrospective study was done to correlate the imaging appearances of the thymus with results from histologic examinations of thymus tissues,The x 2 test was employed to evaluate the difference of the imaging diagnostic methods.Results:The sensitivities of computerized tomograph (CT) and magnetic resonance imaging (MRI) in detecting thymoma and thymic hyperplasia were significantly superior to conventional radiography (plain radiography and traditional tomography) ( P <0.05),and the difference of sensitivity between CT and MRI was not evident ( P >0.05).As for accuracy,there were no obvious differences among the four imaging diagnostic methods ( P >0.05),Conclusion:Both CT and MRI were better than conventional radiography in the detection of thymus abnormalitias patients with MG,and the accuracy of CT and MRI was similar.Considering of scanning time and cost,we recommend a CT scan of the mediastinum in all patients with MG to avoid delayed diagnosis of thymus abnormalities
出处 《卒中与神经疾病》 2000年第1期34-36,共3页 Stroke and Nervous Diseases
关键词 重症肌无力 胸腺瘤 胸腺增生 CT MRI 诊断 Myasthenia gravis Thymoma Thymic hyperplasia CT MRI
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  • 1Levinson AI ,Wheatley LM. The Thymusand the Pathogenesis of Myasthenia gravis.Clin Immunol Immunopathol,1996,78:1
  • 2Kuzin MI,Shkrob OS,Vetshev PS,et al.Comparative evaluation of diagnostic methods inthymus disease.Khirurgiia,1993,5:3
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