血清肌钙蛋白、C反应蛋白检测在鉴别老年患者急性胸痛的临床价值

Application of serum cardiac troponin I,high-sensitivity C-reactive protein in the elderly with acut thorcalgia

目的探讨检测血清肌钙蛋白I(cTnI)、高敏C反应蛋白(hs-CRP)水平对老年(≥65岁)急诊胸痛患者的诊疗价值。方法 2010年1月～2011年12月,选择100例门诊、急诊接诊的老年急性胸痛患者,采用ELISA法急症测定血清中cTnI、hs-CRP,根据检测结果分析两者在胸痛患者中筛查急性心肌梗死(AMI)的意义。结果 100例患者中,有45例血清cTnI、hs-CRP浓度明显增高,呈阳性改变(45%),其中有18例(40%)发生心肌梗死。结论血清hs-CRP、cTnI可作为门诊、急诊检测老年胸痛患者的血清学指标,可以及早预见AMI的发生,尤其是对症状不典型的局灶性心梗,能够及时进行鉴别诊断,避免误诊、漏诊,进而采取有效的诊断、治疗措施,挽救生命。

Objective： To explore the application of serum cardiac troponin I （cTnI）, high - sensitive C -reactive pro- tein（ hs- C RP ） in elderly patients （age ≥65 ） with acute thorcalgia. Methods：From January 2010 to December 2011, 100 eases of the outpatient and emergency admissions of elderly patients with aeute chest pain were selected. The concen- trations of cTnI and hs -CRP were determined using Enzyme Linked Immuno Sorbent Assay （ELISA） and were compared in this group. Correlation analysis was used to examine the relationships between serum eTnI, hs -CRP, and sereen for acute myocardial infarction （ AMI ）of patients with chest pain. Results： In the 100 patients, it was found that 45 eases of serum cTnI, hs -CRP concentrations were significantly higher, and had the positive change. There were 18 eases （ 28 / 6% ） of the occurrence of myocardial infarction in the 45 patients. Conclusion： The serum hs -CRP and eTnI can be used for the detection of aged patients with chest pain in the outpatient and emergeney department of serology, and for early prediction of the occurrence of AMI, especially for atypical symptoms of focal myocardial infarction, so that timely diagnosis can be made for the treatment and the patient＇s life can be saved.