超敏C-反应蛋白联合白细胞检测在新生儿细菌感染性疾病中的应用

Appliacation of hs-CRP combined WBC detection in neonatal bacterial infectious diseases

目的探讨超敏C-反应蛋白(hs-CRP)联合白细胞(WBC)计数检测在新生儿细菌感染诊断中的意义。方法对48例发生细菌感染新生儿(感染组)及40例无感染病症新生儿(非感染组)进行血常规和hs-CRP测定。结果感染组与非感染组比较,hs-CRP和WBC均明显升高,差异有统计学意义(P<0.05)。感染组hs-CRP检测阳性为40例,血常规检测阳性为31例,二者联合检测阳性为44例。结论 hs-CRP联合WBC计数检测对新生儿细菌感染性疾病的早期诊断有一定的价值。

Objective To evaluate the cilnical significance of the detection of high sensitivity C-reactive protein （hs-CRP） and white blood cell （WBC） in diagnosing neonatal bacterial infections. Methods hs-CRP and WBC were detected in 48 neonatal of bacterial infectious diseases and 40 healthy neonatais. Results The level of hs-CRP and WBC count in the infection group were significantly higher than those of non-infection group with statistical differ- ence between two groups（P〈0.05）. In the infection group, the positive hs-CRP was in 40 cases, the positive blood routine was in 31 cases and the positive combined detection was in 44 cases. Conclusion The combined determination of hs-CRP and WBC has certain value for the diagnosis of neonatal bacterial infectious diseases.