门冬氨酸钾镁治疗心律失常的疗效评价

Evaluation of curative effect of potassium magnesium aspartate in treating arrhythmia

目的 评价门冬氨酸钾镁治疗各种心律失常的临床疗效。方法 将 170例心律失常患者随机、单盲分为 2组 :治疗组 (96例 )在常规治疗的基础上 (不包括抗心律失常药物 )加门冬氨酸钾镁 (2 0～ 30ml,静脉滴注 ,2周 ) ,而对照组在常规治疗的基础上加能量合剂。用药前后用常规 12导联心电图和间断 2 4小时动态心电图监测心率和心律的变化 ,并密切观察病人临床症状和体征。结果 治疗组的总有效率明显高于对照组 (分别为92 %和 5 1% ,P<0 0 1) ,治疗组房性和室性心律失常的总有效率分别为 85 %和 95 % (P >0 0 5 ) ,治疗组单纯心律失常和心力衰竭伴心律失常的总有效率分别为 89%和 94% (P >0 0 5 )。结论 门冬氨酸钾镁是治疗各种心律失常包括心力衰竭伴心律失常有效而安全的药物。

Objective To evaluate the clinical efficacy of potassium magnesium aspartate in treating various arrhythmia.Methods Conventional 12-lead ECG and interval 24 hour DCG were used to monitor the changes of heart rate and rhgthm of patients in the treatment group(using potassium magnesium aspartate) and the patients in conventional therapy group(using energy mixture).Clinical symptoms and signs of patients were also observed in the meanwhile.Results The total effective rate of treatment group was significantly higher than that in control group(92%vs.51%,P<0 01).The total effective rates for atrial and ventricular arrhythmia in the treatment group were 85%and 96%(P>0 05)。The total effective rates for rates for simple arrhythmia and congestive heart failure with arrhythmia in the treatment group were 89% and 94% (P>0 05).Conclusion Potassium magnesium aspartate is an effective and safe drug for treatment of various arrhythmia including congestive heart failure with arrhythmia.