微孔多聚糖止血球在全髋关节置换中的应用

Application of microporous polysaccharide hemospheres in total hip arthroplasty

背景:髋关节置换是目前骨科开展的较成熟手术,但暴露大,出血较多,临床需一种理想止血材料及方法来减少患者治疗过程中的出血。目的:观察微孔多聚糖止血球在全髋关节置换中的止血作用。方法:53例行全髋关节置换的患者随机分为观察组25例和对照组28例,对照组采用传统局部止血,观察组采用传统局部止血加微孔多聚糖止血球止血。比较两组在置换后引流量、置换后24h输血量、置换前及置换后第1天复查血红蛋白降低值的区别。结果与结论:观察组在置换后引流量、置换后24h输血量、置换前及置换后第1天复查血红蛋白下降量等方面较对照组显著减少(P<0.05)。提示微孔多聚糖止血球在全髋关节置换中有较好止血效果。

BACKGROUND： Hip replacement is a mature orthopedic surgery, but it has disadvantage of large exposure and more bleeding. We need an ideal hematostatic material and method to reduce bleeding during the treatment in patients. OBJECTIVE： To observe the hemostasis of microporous polysaccharide hemospheres （MPH） in total hip arthroplasty （THA）. METHODS： Totally 53 patients who treated with THA were randomly divided into experimental group （25 cases） and the control group （28 cases）. Conventional topical hemostatic was used in the control group. Conventional topical hemostatic and microporous polysaccharide hemispheres were used in the experimental group. Postoperative drainage, postoperative （24 hours） amount of blood transfusion, reduction value of hemoglobin at preoperative and at the first day postoperative were compared between the two groups. RESULTS AND CONCLUSION： Postoperative drainage, postoperative （24 hours） amount of blood transfusion, reduction value of hemoglobin at preoperative and at the first day postoperative in the experimental group were significantly lower than those in the control group （P 〈 0.05）. It is indicated that MPH has a better hemostatic effect in THA.