摘要
以对甲基苯胺、氟硼酸为主要原料,经西曼反应制得对氟甲苯,再经硝酸氧化反应合成对氟苯甲酸。研究了硝酸氧化的工艺,硝酸氧化的最优条件为:硝酸的质量分数为30%,硝酸氧化温度为110℃,反应压力为1.0 MPa,反应时间选择为2.0 h。硝酸氧化的产率为85%。
The p - fluorobenzoic acid was synthesized via oxidation with nitric acid. The optimum conditions for oxidation were as follows ： the oxidation temperature was 110℃, the oxidation pressure was 1.0 MPa, the concentration of nitric acid was 30% and the react time was 2 h. The productivity of oxidation was 85%.
出处
《有机氟工业》
CAS
2012年第2期5-6,59,共3页
Organo-Fluorine Industry
基金
国家自然科学基金(No.20861003)
贵州省工业攻关项目黔科合GY字([2010]3014)
关键词
对氟苯甲酸
硝酸
氧化
p - tluorobenzoic acid
nitric acid
oxidation
